HORDB

ID: hor002693
Uniprot ID: H2KZL2
Protein name: NLP-9
Gene name: nlp-9
Organism: Caenorhabditis elegans
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: DQAAALPYYLYE
Length: 12(63-74)
Propeptide: MDRFATRFIALLLVLLQIGSIFATPIAEAQGAPEDVDDRRELEKRGGARAFYGFYNAGNSKRDQAAALPYYLYEKRGGGRAFNHNANLFRFDKRGGGRAFAGSWSPYLERFYDYKRSSYPVYFSDNSYY
Signal peptide: MDRFATRFIALLLVLLQIGSIFA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002693_AF2.pdb

hor002693_ESM.pdb

Mass:	161295	Formula:	C67H93N13O21
Absent amino acids:	CFGHIKMNRSTVW	Common amino acids:	AY
pI:	3.55	Basic residues:	0
Polar residues:	3	Hydrophobic residues:	5
Hydrophobicity:	-25	Boman Index:	-622
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	90
Instability Index:	2921.67	Extinction Coefficient cystines:	4470
Absorbance 280nm:	406.36

PubMed ID: 17564681
Title: Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL-21)-deficient Caenorhabditis elegans as analyzed by mass spectrometry.